This is exactly what I was considering it for; I’m 99.9% certain that this can be done with Keyboard Maestro, Karabiner, or, longshot, Better Touch Tool. KM and Kb simply listen for signal codes from any device (general or device-specific), and can then be assigned to keystrokes or complex macros; BTT can do all the same, and different/more, but seems to be restricted to supporting devices piecemeal or only if they strictly adhere to the HID...
