I simply soak my silicone tips in soapy water for a while, then "flush" the gunk out with a moist Q-tip. My IEMs have removable filters so they get a shallow wet clean + dry too. That said, I haven't used the IEMs in... I don't know, maybe 10 months or so.
For headphones, simple lint free cloth wipes. For leather pads, mostly dry wipes with lint free cloth, slightly moist once in a while too though (like once in two-ish months).