Another benefit worth mentioning is that the cameo requires the use of a stabilizer of some type to cut fabric, the accu quilt does not. You wouldn't want to make a quilt with stiffened fabric, it's good for appliqué though.
LinrenCool, Thanks @Karen , @Molly , and @Lindsay for the details! Sounds a lot better. We'll give AccuQuilt a call and see what their minimum order quantities look like.